The role of the endogenous opiates as regulators of appetite 1 ’ 2

نویسندگان

  • John E. Morley
  • Allen S. Levine
  • Oliver Wendell Holmes
چکیده

The popular view of the major function of the opiates is that they produce analgesia. Much evidence has been accumulated that the endogenous opiates play an integral role in the central regulation of appetite. We postulate that the major effect of the endogenous opiates is to induce the feeding drive with their analgesic properties representing an epiphenomenon. Am J Cli,, Nuir 1982;35:757-76l.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ENDOGENOUS RELEASE OF OPIATES BY REPETITIVE ELECTRICAL FIELD STIMULATION IN THE GUINEA-PIG AND RAT ILEAL LONGITUDINAL MUSCLE

The effect of repetitive electrical field stimulation and the response of the guinea-pig and rat ileal longitudinal muscle to single pulse stimulations was examined. Single pulse field stimulation produced twitch contraction which was inhibited by repetitive field stimulation (10 Hz, 40V, 0.5 msec for 5 m). This inhibition was largely, though never completely, reversed by naloxone. Contrac...

متن کامل

THE ROLE OF NON-ADRENERGIC NON-CHOLINERGIC SYSTEM IN THE PERISTALTIC REFLEX OF GUINE A PIG ILEUM

The effect of some endogenous components -endogenous opiates, cholecystokinin (CCK), vasoactive intestinal polypeptide (VIP) and somatostatin-as inhibitory or excitatory transmitters in the local nervous pathways involved in peristaltic responses was examined. The peristaltic reflex was studied using a modification of the Trendelenberg preparation. In each preparation, the luminal distens...

متن کامل

Growth of Lily Bulblets In Vitro, a Review

In micropropagation of lily, preferably bulblets should be produced: Because bulblets are compact and robust, they are much easier to handle and to plant in soil than shoots. In this review, the various factors that determine bulblet growth in vitro are discussed. Gibberellins, jasmonates (JA) and abscisic acid (ABA) are the major identified plant growth regulators (PGRs) for storage organ form...

متن کامل

Endocannabinoids and the regulation of body fat: the smoke is clearing.

Endocannabinoids, endogenous ligands of cannabinoid receptor type 1 (CB1), have emerged as novel and important regulators of energy homeostasis. A report in this issue demonstrates reduced body weight, fat mass, and appetite in CB1-/- mice. Examination of the underlying mechanisms reveals a dual role for endocannabinoids as they affect both appetite and peripheral lipolysis.

متن کامل

Morphine in Plasma and Cerebrospinal Fluid of Patients Addicted to Opiates Undergoing Surgery: High-performance Liquid Chromatography Method

Background: The prevalence of opium addiction among Iranians is considerable. Since endogenous opioid systems may be altered as a consequence of addiction, it is very important to determine the plasma and cerebrospinal fluid (CSF) levels of morphine in Iranian patients addicted to opiates who will undergo surgery.Methods: We obtained CSF and plasma samples from 50 volunteers with an established...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2005